Thrombin-Mediated Degradation of Human Cardiac Troponin T

201784 citationsJournal Articlebronze Open Access

Authors

Ivan A. Katrukha · Lomonosov Moscow State University

Alexander E Kogan · HyTest (Finland)

Alexandra V Vylegzhanina · HyTest (Finland)

Marina V. Serebryakova · Lomonosov Moscow State University

Ekaterina V Koshkina · Moscow City Hospital No 29

A. Bereznikova · HyTest (Finland)

Alexey G Katrukha

Abstract

The results of this study suggest that the 29-kDa fragment of cTnT in AMI serum samples mainly appears due to the cleavage by thrombin during serum sample preparation.

Topics & Keywords

Calpain Protease Function and Regulation Signaling Pathways in Disease Blood properties and coagulation

Publication Details

Published in: Clinical Chemistry

Volume 63, Issue 6, pp. 1094-1100

DOI: 10.1373/clinchem.2016.266635

Field-Weighted Citation Impact: 3.61

Command Palette

Thrombin-Mediated Degradation of Human Cardiac Troponin T

Authors

Abstract

Topics & Keywords

Publication Details