The Use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women

19951,509 citationsJournal Articlebronze Open Access

Authors

Graham A. Colditz · Brigham and Women's Hospital

Susan E. Hankinson · Harvard University

David J. Hunter · Brigham and Women's Hospital

Walter C. Willett · Harvard University

JoAnn E. Manson · Brigham and Women's Hospital

Meir J. Stampfer · Harvard University

Charles H. Hennekens

Abstract

The addition of progestins to estrogen therapy does not reduce the risk of breast cancer among postmenopausal women. The substantial increase in the risk of breast cancer among older women who take hormones suggests that the trade-offs between risks and benefits should be carefully assessed.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 332, Issue 24, pp. 1589-1593

DOI: 10.1056/nejm199506153322401

Field-Weighted Citation Impact: 97.52