Overexpression of the Cytokine BAFF and Autoimmunity Risk

2017386 citationsJournal Articlebronze Open Access

Authors

Maristella Steri · Institute of Genetic and Biomedical Research

Valeria Orrù · Institute of Genetic and Biomedical Research

Maria Laura Idda · Institute of Genetic and Biomedical Research

Maristella Pitzalis · Institute of Genetic and Biomedical Research

Mauro Pala · Institute of Genetic and Biomedical Research

Ilenia Zara · Center for Advanced Studies Research and Development in Sardinia

Abstract

A TNFSF13B variant was associated with multiple sclerosis and SLE, and its effects were clarified at the population, cellular, and molecular levels. (Funded by the Italian Foundation for Multiple Sclerosis and others.).

Topics & Keywords

Systemic Lupus Erythematosus Research Cytokine Signaling Pathways and Interactions Systemic Sclerosis and Related Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 376, Issue 17, pp. 1615-1626

DOI: 10.1056/nejmoa1610528

Field-Weighted Citation Impact: 40.22