Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes

2017112 citationsJournal Articlegreen Open Access

Authors

Pietro Enea Lazzerini · University of Siena

Franco Laghi‐Pasini · University of Siena

Iacopo Bertolozzi · Accademia di Belle Arti di Carrara

Gabriella Morozzi · University of Siena

Sauro Lorenzini · University of Siena

Antonella Simpatico · University of Siena

Enrico Selvi ·

Abstract

The data are first to show that systemic inflammation via elevated IL-6 levels may represent a novel QT-prolonging risk factor contributing to TdP occurrence in the presence of other classical risk factors. If confirmed, this could open new avenues in antiarrhythmic therapy.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Atrial Fibrillation Management and Outcomes Cardiac Arrhythmias and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Heart

Volume 103, Issue 22, pp. 1821-1829

DOI: 10.1136/heartjnl-2016-311079

Field-Weighted Citation Impact: 8.03