Body mass index and breast cancer survival: a Mendelian randomization analysis

201767 citationsJournal Articlehybrid Open Access

Authors

Qi Guo · University of Cambridge

Stephen Burgess · University of Cambridge

Constance Turman · Harvard University

Manjeet K. Bolla · University of Cambridge

Qin Wang · University of Cambridge

Michael Lush · University of Cambridge

Jean Abraham ·

Abstract

Our findings suggest a causal effect of increased BMI on reduced breast cancer survival for ER-positive breast cancer. There is no evidence of a causal effect of higher BMI on survival for ER-negative breast cancer cases.

Topics & Keywords

Cancer Risks and Factors Genetic Associations and Epidemiology Nutritional Studies and Diet

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Epidemiology

Volume 46, Issue 6, pp. 1814-1822

DOI: 10.1093/ije/dyx131

Field-Weighted Citation Impact: 2.95