Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

20172,143 citationsJournal Articlebronze Open Access

Authors

Christopher W. Seymour

Foster Gesten · New York State Department of Health

Hallie C. Prescott · VA Center for Clinical Management Research

Marcus Friedrich · New York State Department of Health

Theodore J. Iwashyna · University of Michigan–Ann Arbor

Gary Phillips · Island Peer Review Organization

Stanley Lemeshow · The Ohio State University

Abstract

More rapid completion of a 3-hour bundle of sepsis care and rapid administration of antibiotics, but not rapid completion of an initial bolus of intravenous fluids, were associated with lower risk-adjusted in-hospital mortality. (Funded by the National Institutes of Health and others.).

Topics & Keywords

Sepsis Diagnosis and Treatment Nosocomial Infections in ICU Disaster Response and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 376, Issue 23, pp. 2235-2244

DOI: 10.1056/nejmoa1703058

Field-Weighted Citation Impact: 127.31