Intraplaque Hemorrhage and Progression of Coronary Atheroma

20031,469 citationsJournal Articlebronze Open Access

Authors

Frank D. Kolodgie · Armed Forces Institute of Pathology

Herman K. Gold · Massachusetts General Hospital

Allen Burke · Armed Forces Institute of Pathology

David R. Fowler · University of Maryland, Baltimore

Howard S. Kruth

Deena K. Weber · Armed Forces Institute of Pathology

Andrew Farb · Armed Forces Institute of Pathology

Abstract

By contributing to the deposition of free cholesterol, macrophage infiltration, and enlargement of the necrotic core, the accumulation of erythrocyte membranes within an atherosclerotic plaque may represent a potent atherogenic stimulus. These factors may increase the risk of plaque destabilization.

Topics & Keywords

Atherosclerosis and Cardiovascular Diseases Blood properties and coagulation Systemic Lupus Erythematosus Research

Publication Details

Published in: New England Journal of Medicine

Volume 349, Issue 24, pp. 2316-2325

DOI: 10.1056/nejmoa035655

Field-Weighted Citation Impact: 12.92

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Intraplaque Hemorrhage and Progression of Coronary Atheroma

Authors

Abstract

Topics & Keywords

Publication Details