A Randomized, Controlled Trial of Magnesium Sulfate for the Prevention of Cerebral Palsy

2008691 citationsJournal Articlebronze Open Access

Authors

Dwight J. Rouse · University of Alabama at Birmingham

Deborah G. Hirtz · National Institute of Neurological Disorders and Stroke

Elizabeth Thom · George Washington University

Michael W. Varner · University of Utah

Catherine Y. Spong

Brian M. Mercer · University of Tennessee at Knoxville

Jay D. Iams · The Ohio State University

Abstract

Fetal exposure to magnesium sulfate before anticipated early preterm delivery did not reduce the combined risk of moderate or severe cerebral palsy or death, although the rate of cerebral palsy was reduced among survivors. (ClinicalTrials.gov number, NCT00014989.)

Topics & Keywords

Cerebral Palsy and Movement Disorders Preterm Birth and Chorioamnionitis Infant Development and Preterm Care

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 359, Issue 9, pp. 895-905

DOI: 10.1056/nejmoa0801187

Field-Weighted Citation Impact: 19.56