Emerging Safety of Intramedullary Transplantation of Human Neural Stem Cells in Chronic Cervical and Thoracic Spinal Cord Injury

2017147 citationsJournal Article

Authors

Allan D. Levi · University of Maryland, Baltimore

David O. Okonkwo · University of Maryland, Baltimore

Paul Park · University of Maryland, Baltimore

Arthur L. Jenkins · University of Maryland, Baltimore

Shekar N. Kurpad · University of Maryland, Baltimore

Ann M. Parr · University of Maryland, Baltimore

Aruna Ganju

Abstract

A total cell dose of 20 M cells via 4 and up to 40 M cells via 8 perilesional intramedullary injections after thoracic and cervical SCI respectively proved safe and feasible using a manual injection technique.

Topics & Keywords

Spinal Cord Injury Research Nerve Injury and Rehabilitation Neurogenetic and Muscular Disorders Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurosurgery

Volume 82, Issue 4, pp. 562-575

DOI: 10.1093/neuros/nyx250

Field-Weighted Citation Impact: 8.05