Parental Perspectives on Whole-Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility

201746 citationsJournal Article

Authors

Janet Malek · Baylor College of Medicine

Melody J. Slashinski · Texas Children's Hospital

Jill O. Robinson · Baylor College of Medicine

Amanda M. Gutierrez · Baylor College of Medicine

D. Williams Parsons · Baylor College of Medicine

Sharon E. Plon · Baylor College of Medicine

Laurence B. McCullough

Abstract

Parents of pediatric cancer patients perceive WES to have broad utility, including psychological and pragmatic utility, even if there is no direct impact on clinical care. Further work will need to consider how the value of genomic information should be characterized, how risks and benefits should be described, and how these results should inform recommendations and decisions about using WES.

Topics & Keywords

Genomics and Rare Diseases BRCA gene mutations in cancer Childhood Cancer Survivors' Quality of Life

UN Sustainable Development Goals

Gender equality

Publication Details

Published in: JCO Precision Oncology

Volume 1, Issue 1, pp. 1-10

DOI: 10.1200/po.17.00010

Field-Weighted Citation Impact: 3.36