The relationship between circulating mitochondrial DNA and inflammatory cytokines in patients with major depression

2017103 citationsJournal Articlehybrid Open Access

Authors

Yuki Kageyama · RIKEN Center for Brain Science

Takaoki Kasahara · RIKEN Center for Brain Science

Masaki Kato · Kansai Medical University

Shiho Sakai · Kansai Medical University

Yasuhiko Deguchi · Osaka City University

Munehide Tani · Osaka Nishi Clinic

Kenji Kuroda ·

Abstract

The present findings coincide with our hypothesis that circulating mtDNA contributes to the inflammation in MDD. Further studies are needed to conclude whether plasma mtDNA would be a biomarker of mood disorders.

Topics & Keywords

Tryptophan and brain disorders Stress Responses and Cortisol Neuroinflammation and Neurodegeneration Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Affective Disorders

Volume 233, pp. 15-20

DOI: 10.1016/j.jad.2017.06.001

Field-Weighted Citation Impact: 2.43