Autoantibodies against BAFF, APRIL or IL21 - an alternative pathogenesis for antibody-deficiencies?

201711 citationsJournal Articlegold Open Access

Authors

Marian-Christopher Pott · University Medical Center Freiburg

Natalie Frede · University Medical Center Freiburg

Jennifer Wanders · University College London

Lennart Hammarström · Karolinska Institutet

Erik-Oliver Glocker · Klinikum Brandenburg

Cristina Glocker · University Medical Center Freiburg

Fariba Tahami

Abstract

Whilst statistical analysis of ELISA results showed significant differences between patients and healthy controls, in our set of patients functional tests yielded no evidence for an involvement of autoantibodies against BAFF, APRIL, or IL-21 in the pathogenesis of CVID or sIgAD.

Topics & Keywords

Immunodeficiency and Autoimmune Disorders Blood disorders and treatments Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Immunology

Volume 18, Issue 1, pp. 34-34

DOI: 10.1186/s12865-017-0217-9

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