Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review

2017234 citationsReviewgold Open Access

Authors

Eric Peter Thelin · University of Cambridge

Frederick A. Zeiler · University of Manitoba

Ari Ercole · University of Cambridge

Stefania Mondello · University of Messina

András Büki · MTA-SZTE Research Group on Artificial Intelligence

Bo‐Michael Bellander · Karolinska Institutet

Adel Helmy

Abstract

Serial sampling of brain-specific proteins in serum reveals different temporal trajectories that should be acknowledged. Proteins with shorter serum availability, like S100B, may be superior to proteins such as NF-L in detection of secondary harmful events when monitoring patients with TBI.

Topics & Keywords

Traumatic Brain Injury and Neurovascular Disturbances Traumatic Brain Injury Research S100 Proteins and Annexins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Neurology

Volume 8, pp. 300-300

DOI: 10.3389/fneur.2017.00300

Field-Weighted Citation Impact: 12.30