The Involvement of ERCC2/XPD and ERCC6/CSB Wild Type Alleles in Protection Against Aging and Cancer

20177 citationsJournal Article

Authors

Nataliya V. Savina · Institute of Genetics and Cytology of the National Academy of Sciences of Belarus

Н. В. Никитченко · Institute of Genetics and Cytology of the National Academy of Sciences of Belarus

Tatyana D. Kuzhir · Institute of Genetics and Cytology of the National Academy of Sciences of Belarus

A.I. Rolevich · N.N. Alexandrov National Cancer Centre

S. А. Krasny · N.N. Alexandrov National Cancer Centre

Р. И. Гончарова · Institute of Genetics and Cytology of the National Academy of Sciences of Belarus

Abstract

Homozygous wild type alleles encoding XPD and CSB proteins with optimal properties were shown to affect human lifespan, risk of developing bladder cancer, its progression and recurrence under certain conditions.

Topics & Keywords

Epigenetics and DNA Methylation CRISPR and Genetic Engineering Cancer Research and Treatments

Publication Details

Published in: Current Aging Science

Volume 11, Issue 1, pp. 45-54

DOI: 10.2174/1874609810666170707101548

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The Involvement of ERCC2/XPD and ERCC6/CSB Wild Type Alleles in Protection Against Aging and Cancer

Authors

Abstract

Topics & Keywords

Publication Details