Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study

201772 citationsJournal Articlehybrid Open Access

Authors

Khurum Khan · Royal Marsden NHS Foundation Trust

Mihaela Rata · Institute of Cancer Research

David Cunningham · Royal Marsden NHS Foundation Trust

Dow‐Mu Koh · Cancer Research UK

Nina Tunariu · Royal Marsden Hospital

Jens C. Hahne · Institute of Cancer Research

George Vlachogiannis

Abstract

Combining DCE-MRI and ctDNA predicts duration of anti-angiogenic response to regorafenib and may improve patient management with potential health/economic implications.

Topics & Keywords

Hepatocellular Carcinoma Treatment and Prognosis Cancer Genomics and Diagnostics Radiomics and Machine Learning in Medical Imaging

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 67, Issue 8, pp. 1484-1492

DOI: 10.1136/gutjnl-2017-314178

Field-Weighted Citation Impact: 5.63