Effect of microRNA-135a on Cell Proliferation, Migration, Invasion, Apoptosis and Tumor Angiogenesis Through the IGF-1/PI3K/Akt Signaling Pathway in Non-Small Cell Lung Cancer

2017126 citationsJournal Articlegold Open Access

Authors

Yufei Zhou · Ningbo Dahongying University

Jiangtao Li · Yantai Laiyang Central Hospital

Dongfeng Wang · Ningbo Dahongying University

Quanxing Li · Ningbo Dahongying University

Abstract

These findings indicated that miR-135a promotes cell apoptosis and inhibits cell proliferation, migration, invasion and tumor angiogenesis by targeting IGF-1 gene through the IGF-1/PI3K/Akt signaling pathway in NSCLC.

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Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 42, Issue 4, pp. 1431-1446

DOI: 10.1159/000479207

Field-Weighted Citation Impact: 5.78

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Effect of microRNA-135a on Cell Proliferation, Migration, Invasion, Apoptosis and Tumor Angiogenesis Through the IGF-1/PI3K/Akt Signaling Pathway in Non-Small Cell Lung Cancer

Authors

Abstract

Topics & Keywords

Publication Details