Neutrophil extracellular traps in ischemic stroke thrombi

2017499 citationsJournal Article

Authors

Elodie Laridan · Research Institute for Chromatography

Frederik Denorme · Research Institute for Chromatography

Linda Desender · Research Institute for Chromatography

Olivier François · AZ Groeninge

Tommy Andersson · Karolinska Institutet

Hans Deckmyn · KU Leuven

Karen Vanhoorelbeke

Abstract

Neutrophils and NETs form important constituents of cerebral thrombi. Targeting of NETs with DNase 1 might have prothrombolytic potential in treatment of acute ischemic stroke. Ann Neurol 2017;82:223-232.

Topics & Keywords

Neutrophil, Myeloperoxidase and Oxidative Mechanisms S100 Proteins and Annexins Acute Ischemic Stroke Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 82, Issue 2, pp. 223-232

DOI: 10.1002/ana.24993

Field-Weighted Citation Impact: 11.42