The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

20174,093 citationsJournal Articlegold Open Access

Authors

Lu Zhang · Jiangsu Province Hospital

Jianghao Xu · Jiangsu Province Hospital

Xuan Zhang · Jiangsu Province Hospital

Yi Zhang · Jiangsu Province Hospital

Lu Wang · Nanjing Medical University

Xiaoxu Huang · Nanjing Medical University

Zekuan Xu ·

Abstract

FOXP3 expression was associated with degree of gastric cancer differentiation. In addition, upregulated and ectopic tumoral FOXP3 can promote gastric cancer proliferation, migration, and invasion, partly through the TGF-β pathway.

Topics & Keywords

Immune Cell Function and Interaction Cancer-related molecular mechanisms research T-cell and B-cell Immunology

Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 42, Issue 5, pp. 1739-1754

DOI: 10.1159/000479442

Field-Weighted Citation Impact: 144.64

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The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

Authors

Abstract

Topics & Keywords

Publication Details