Temporal trends in sperm count: a systematic review and meta-regression analysis

20171,306 citationsReviewbronze Open Access

Authors

Hagai Levine · Hebrew University of Jerusalem

Niels Jørgensen · University of Copenhagen

Anderson Joel Martino‐Andrade · Universidade Federal do Paraná

Jaime Mendiola · Universidad de Murcia

Dan Weksler-Derri · Ben-Gurion University of the Negev

Irina Mindlis · Icahn School of Medicine at Mount Sinai

Rachel Pinotti

Abstract

This comprehensive meta-regression analysis reports a significant decline in sperm counts (as measured by SC and TSC) between 1973 and 2011, driven by a 50-60% decline among men unselected by fertility from North America, Europe, Australia and New Zealand. Because of the significant public health implications of these results, research on the causes of this continuing decline is urgently needed.

Topics & Keywords

Sperm and Testicular Function Reproductive Health and Technologies Ovarian function and disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Human Reproduction Update

Volume 23, Issue 6, pp. 646-659

DOI: 10.1093/humupd/dmx022

Field-Weighted Citation Impact: 118.89