Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis

2017216 citationsReviewhybrid Open Access

Authors

Alhadi Almangush · University of Helsinki

Ilkka Heikkinen · University of Helsinki

Antti Mäkitie · Helsinki University Hospital

Ricardo D. Coletta · Universidade Estadual de Campinas (UNICAMP)

Esa Läärä · University of Oulu

Ilmo Leivo · University of Turku

Tuula Salo ·

Abstract

Numerous biomarkers have been presented as useful prognosticators for OTSCC, but the quality of the conduct and reporting of original studies is overall unsatisfactory which does not allow reliable conclusions. The value of two biomarkers (VEGF-A and cyclin D1) should be validated in a multicentre study setting following REMARK guidelines.

Topics & Keywords

Head and Neck Cancer Studies Colorectal and Anal Carcinomas Salivary Gland Tumors Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Cancer

Volume 117, Issue 6, pp. 856-866

DOI: 10.1038/bjc.2017.244

Field-Weighted Citation Impact: 13.28