Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer

2017765 citationsJournal Article

Authors

K.C. Allen Chan · Prince of Wales Hospital

John K. S. Woo · Chinese University of Hong Kong

Ann D. King · Chinese University of Hong Kong

Benny Zee · Hong Kong Jockey Club

W.K. Lam · Chinese University of Hong Kong

Stephen L. Chan · Chinese University of Hong Kong

Sam W.I. Chu ·

Abstract

Analysis of EBV DNA in plasma samples was useful in screening for early asymptomatic nasopharyngeal carcinoma. Nasopharyngeal carcinoma was detected significantly earlier and outcomes were better in participants who were identified by screening than in those in a historical cohort. (Funded by the Kadoorie Charitable Foundation and the Research Grants Council of the Hong Kong government; ClinicalTrials.gov number, NCT02063399 .).

Topics & Keywords

Viral-associated cancers and disorders Cholangiocarcinoma and Gallbladder Cancer Studies Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 377, Issue 6, pp. 513-522

DOI: 10.1056/nejmoa1701717

Field-Weighted Citation Impact: 29.84