Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

2017647 citationsReviewgreen Open Access

Authors

Scott Neu · University of Southern California

Judy Pa · University of Southern California

Walter A. Kukull · University of Washington

Duane Beekly · University of Washington

Amanda Kuzma · University of Pennsylvania

Prabhakaran Gangadharan · University of Pennsylvania

Li-San Wang ·

Abstract

Contrary to long-standing views, men and women with the APOE ε3/ε4 genotype have nearly the same odds of developing AD from age 55 to 85 years, but women have an increased risk at younger ages.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Blood Pressure and Hypertension Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Neurology

Volume 74, Issue 10, pp. 1178-1178

DOI: 10.1001/jamaneurol.2017.2188

Field-Weighted Citation Impact: 32.92