Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts

2017357 citationsReviewgold Open Access

Authors

Fengming Yang · Center for Personalized Cancer Treatment

Zhiqiang Ning · Wujiang District People's Hospital

Ling Ma · Nanjing Medical University

Weitao Liu · Nanjing Medical University

Chuchu Shao · Jiangsu Province Hospital

Yongqian Shu · Nanjing Medical University

Hua Shen ·

Abstract

Finding of exosomal miRNA secretion provides novel insights into communication among CAFs, NFs, and cancer cells. MicroRNA dysregulation is also involved in the whole processes of CAF formation and function. Dysregulation of miRNAs in CAFs can affect the secretory phenotype of the latter cells.

Topics & Keywords

Extracellular vesicles in disease MicroRNA in disease regulation Circular RNAs in diseases

UN Sustainable Development Goals

No povertyGood health and well-being

Publication Details

Published in: Molecular Cancer

Volume 16, Issue 1, pp. 148-148

DOI: 10.1186/s12943-017-0718-4

Field-Weighted Citation Impact: 13.54