Adverse effects & drug load of antiepileptic drugs in patients with epilepsy

201759 citationsJournal Articlediamond Open Access

Authors

Sheffali Gulati · All India Institute of Medical Sciences

Abstract

Polytherapy with combination of greater than or equal to three AEDs was associated with higher AEs and lower seizure control as compared to both monotherapy and combination of two AEDs. AEs did not correlate with AED load, seizure type, gender and age of the patients but were associated with both numbers of AEDs as well as seizure frequency in PWE.

Topics & Keywords

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Indian Journal of Medical Research

Volume 145, Issue 3, pp. 317-326

DOI: 10.4103/ijmr.ijmr_710_15

Field-Weighted Citation Impact: 2.36

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