Concomitant vascular and neurodegenerative pathologies double the risk of dementia

2017177 citationsJournal Article

Authors

Mahmoud Reza Azarpazhooh · Western University

Abolfazl Avan · Mashhad University of Medical Sciences

Lauren E. Cipriano · Western University

David G. Muñoz · St. Michael's Hospital

Luciano A. Sposato · Western University

Vladimir Hachinski · Western University

Abstract

Patients with mixed pathologies have nearly twice the incremental risk of dementia compared with patients with only Alzheimer-type lesions. Consequently, many cases of dementia could be prevented or delayed by targeting the vascular component.

Topics & Keywords

Dementia and Cognitive Impairment Research Neurological Disease Mechanisms and Treatments Nutritional Studies and Diet

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alzheimer s & Dementia

Volume 14, Issue 2, pp. 148-156

DOI: 10.1016/j.jalz.2017.07.755

Field-Weighted Citation Impact: 9.82