Branched-chain amino acid metabolism in cancer

2017302 citationsReviewhybrid Open Access

Authors

Abstract

Both oncogenic mutations and cancer tissue-of-origin influence BCAA metabolism and expression of BCAA-associated metabolic enzymes. These new discoveries need to be taken into consideration during the development of new cancer therapies that target BCAA metabolism.

Topics & Keywords

Epigenetics and DNA Methylation Cancer, Hypoxia, and Metabolism RNA modifications and cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Current Opinion in Clinical Nutrition & Metabolic Care

Volume 21, Issue 1, pp. 64-70

DOI: 10.1097/mco.0000000000000430

Field-Weighted Citation Impact: 9.18