Purification of influenza virus‐like particles using sulfated cellulose membrane adsorbers

201738 citationsJournal Articlehybrid Open Access

Authors

Sofia B. Carvalho · Instituto de Biologia Experimental e Tecnológica

Ana Raquel Fortuna · Max Planck Institute for Dynamics of Complex Technical Systems

Michael W. Wolff · Max Planck Institute for Dynamics of Complex Technical Systems

Cristina Peixoto · Instituto de Biologia Experimental e Tecnológica

Paula M. Alves · Instituto de Biologia Experimental e Tecnológica

Udo Reichl · Max Planck Institute for Dynamics of Complex Technical Systems

Abstract

Use of SCMA represents a significant improvement compared with conventional ion exchanger membrane adsorbers. As the method proposed is easily scalable and reduces the number of steps required compared with conventional purification methods, SCMA could qualify as a generic platform for purification of VLP-based influenza vaccines. © 2017 The Authors. <i>Journal of Chemical Technology & Biotechnology</i> published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Topics & Keywords

Protein purification and stability Monoclonal and Polyclonal Antibodies Research SARS-CoV-2 and COVID-19 Research

UN Sustainable Development Goals

Industry, innovation and infrastructure

Publication Details

Published in: Journal of Chemical Technology & Biotechnology

Volume 93, Issue 7, pp. 1988-1996

DOI: 10.1002/jctb.5474

Field-Weighted Citation Impact: 1.90