RNA virus interference via CRISPR/Cas13a system in plants

20181,495 citationsJournal Articlegold Open Access

Authors

Rashid Aman · King Abdullah University of Science and Technology

Zahir Ali · King Abdullah University of Science and Technology

Haroon Butt · King Abdullah University of Science and Technology

Ahmed Mahas · King Abdullah University of Science and Technology

Fatimah Aljedaani · King Abdullah University of Science and Technology

Muhammad Zuhaib Khan · King Abdullah University of Science and Technology

Abstract

Our data indicate that CRISPR/Cas13a can be used for engineering interference against RNA viruses, providing a potential novel mechanism for RNA-guided immunity against RNA viruses and for other RNA manipulations in plants.

Topics & Keywords

CRISPR and Genetic Engineering Plant Virus Research Studies Insect symbiosis and bacterial influences

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Genome biology

Volume 19, Issue 1, pp. 1-1

DOI: 10.1186/s13059-017-1381-1

Field-Weighted Citation Impact: 43.49