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Why are there hotspot mutations in the TP53 gene in human cancers?

2017605 citationsReviewbronze Open Access

Authors

Evan H. Baugh · New York University

Hua Zhu Ke · Rutgers, The State University of New Jersey

Arnold J. Levine · Institute for Advanced Study

Richard Bonneau · Simons Foundation

Chang S. Chan · Rutgers, The State University of New Jersey

Topics & Keywords

Cancer-related Molecular Pathways Cancer Genomics and Diagnostics DNA Repair Mechanisms

Publication Details

Published in: Cell Death and Differentiation

Volume 25, Issue 1, pp. 154-160

DOI: 10.1038/cdd.2017.180

Field-Weighted Citation Impact: 13.21

Why are there hotspot mutations in the TP53 gene in human cancers? | Researchclopedia