Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

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Authors

Mayara Karla dos Santos Nunes · Universidade Federal da Paraíba

Alexandre Sérgio Silva · Universidade Federal da Paraíba

Isabella Wanderley de Queiroga Evangelista · Universidade Federal da Paraíba

João Modesto Filho · Universidade Federal da Paraíba

Cecília Neta Alves Pegado Gomes · Hospital Universitário Lauro Wanderley

Rayner Anderson Ferreira do Nascimento · Centro Universitário Maurício de Nassau

Abstract

Hypermethylation in the promoter of the MTHFR gene is associated with the occurrence of DR and with biochemical, inflammatory and oxidative stress parameters in the context of chronic complications.

Topics & Keywords

Folate and B Vitamins Research Birth, Development, and Health Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Diabetology & Metabolic Syndrome

Volume 9, Issue 1, pp. 84-84

DOI: 10.1186/s13098-017-0284-3

Field-Weighted Citation Impact: 5.75