Impact of Close and Positive Margins in Transoral Laser Microsurgery for Tis–T2 Glottic Cancer

The study indicates that close and positive single superficial margins do not affect DSS. By contrast, all types of margin positivity predict the occurrence of relapses, albeit with different likelihood, depending on stage/margin type. CD margins should be considered as a single risk factor. Use of NBI granted better intraoperative margins definition.