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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

20171,677 citationsJournal Article

Authors

Matthew J. Hangauer · UCSF Helen Diller Family Comprehensive Cancer Center

Vasanthi S. Viswanathan · Broad Institute

Matthew J. Ryan · Broad Institute

Dhruv Bole · University of California, San Francisco

John K. Eaton · Broad Institute

Alexandre Matov

Jacqueline Galeas · University of California, San Francisco

Topics & Keywords

Ferroptosis and cancer prognosis Caveolin-1 and cellular processes Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature

Volume 551, Issue 7679, pp. 247-250

DOI: 10.1038/nature24297

Field-Weighted Citation Impact: 68.04

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition | Researchclopedia

Harshil Dhruv · Translational Genomics Research Institute

Michael E. Berens · Translational Genomics Research Institute

Stuart L. Schreiber · Broad Institute

Frank McCormick · UCSF Helen Diller Family Comprehensive Cancer Center

Michael T. McManus · University of California, San Francisco