A Test-and-Not-Treat Strategy for Onchocerciasis in<i>Loa loa</i>–Endemic Areas

2017305 citationsJournal Articlehybrid Open Access

Authors

Joseph Kamgno · Université de Yaoundé I

Sébastien D. S. Pion · University of Buea

Cédric B. Chesnais · University of Buea

Matthew H. Bakalar · Université de Montpellier

Michael V. D’Ambrosio · University of California, Berkeley

Charles D. Mackenzie · Université de Montpellier

Hugues C. Nana-Djeunga

Abstract

The LoaScope-based test-and-not-treat strategy enabled the reimplementation of community-wide ivermectin distribution in a heretofore "off limits" health district in Cameroon and is a potentially practical approach to larger-scale ivermectin treatment for lymphatic filariasis and onchocerciasis in areas where L. loa infection is endemic. (Funded by the Bill and Melinda Gates Foundation and others.).

Topics & Keywords

Parasitic Diseases Research and Treatment Insect symbiosis and bacterial influences Mosquito-borne diseases and control

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 377, Issue 21, pp. 2044-2052

DOI: 10.1056/nejmoa1705026

Field-Weighted Citation Impact: 14.89