Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients

201736 citationsJournal Articlediamond Open Access

Authors

Mariano Provencio · Hospital Universitario Puerta de Hierro Majadahonda

María Torrente · Hospital Universitario Puerta de Hierro Majadahonda

Virginia Calvo · Hospital Universitario Puerta de Hierro Majadahonda

David Pérez-Callejo · Hospital Universitario Puerta de Hierro Majadahonda

Lourdes Gutiérrez · Hospital Universitario Puerta de Hierro Majadahonda

Fernando Franco · Hospital Universitario Puerta de Hierro Majadahonda

Abstract

The appearance or increase in a unit of the p.T790M allele frequency almost triples the risk of death and progression. This information can be used to design clinical trials aiming to estimate whether T790M positive patients should start second line treatment based on molecular data rather than imaging data.

Topics & Keywords

Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations Molecular Biology Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Oncotarget

Volume 9, Issue 1, pp. 488-494

DOI: 10.18632/oncotarget.22470

Field-Weighted Citation Impact: 1.16