Exosomes from MiR-126-Overexpressing Adscs Are Therapeutic in Relieving Acute Myocardial Ischaemic Injury

2017261 citationsJournal Articlegold Open Access

Authors

Qiancheng Luo · Shanghai Pudong New Area Gongli Hospital

Dongfeng Guo · Shanghai Pudong New Area Gongli Hospital

Guorong Liu · Second Military Medical University

Guo Chen · Shanghai Pudong New Area Gongli Hospital

Hang Min · Shanghai Pudong New Area Gongli Hospital

Mingming Jin

Abstract

The results suggested that the expression of miR-126-enhanced ADSC-derived exosomes prevented myocardial damage by protecting myocardial cells from apoptosis, inflammation, fibrosis, and increased angiogenesis.

Topics & Keywords

Extracellular vesicles in disease Cardiovascular Disease and Adiposity Cardiovascular Effects of Exercise

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 44, Issue 6, pp. 2105-2116

DOI: 10.1159/000485949

Field-Weighted Citation Impact: 9.30