Functional Metabolomics Characterizes a Key Role for <i>N</i> -Acetylneuraminic Acid in Coronary Artery Diseases

2017186 citationsJournal Articlebronze Open Access

Authors

Lei Zhang · China Pharmaceutical University

Tingting Wei · China Pharmaceutical University

Yong Li · Jiangsu University

Jing Li · China Pharmaceutical University

Yong Fan · China Pharmaceutical University

Feng-Qing Huang · China Pharmaceutical University

Yuanyuan Cai ·

Abstract

Functional metabolomics identified a key role for Neu5Ac in acute myocardial infarction, and targeting neuraminidase-1 may represent an unrecognized therapeutic intervention for CAD.

Topics & Keywords

Metabolomics and Mass Spectrometry Studies Eicosanoids and Hypertension Pharmacology Adipose Tissue and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 137, Issue 13, pp. 1374-1390

DOI: 10.1161/circulationaha.117.031139

Field-Weighted Citation Impact: 4.48