A higher CD4/CD8 ratio correlates with an ultralow cell-associated HIV-1 DNA level in chronically infected patients on antiretroviral therapy: a case control study

201733 citationsJournal Articlegold Open Access

Authors

Yongsong Yue · Peking Union Medical College Hospital

Nidan Wang · Chinese Academy of Medical Sciences & Peking Union Medical College

Yang Han · Chinese Academy of Medical Sciences & Peking Union Medical College

Ting Zhu · Chinese Academy of Medical Sciences & Peking Union Medical College

Jing Xie · Peking Union Medical College Hospital

Zhifeng Qiu · Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

After matching baseline HIV-1 DNA levels, a higher CD4/CD8 ratio at week 96 was the only factor associated with an ultralow level of HIV-1 DNA. The CD4/CD8 ratio can be used as an easy biomarker to help monitor patients on ART who will be selected to participate in eradication studies.

Topics & Keywords

HIV Research and Treatment HIV/AIDS Research and Interventions HIV/AIDS drug development and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Infectious Diseases

Volume 17, Issue 1, pp. 771-771

DOI: 10.1186/s12879-017-2866-y

Field-Weighted Citation Impact: 2.09