High‐frequency oscillations are not better biomarkers of epileptogenic tissues than spikes

2017217 citationsJournal Articlegreen Open Access

Authors

Nicolas Roehri · Inserm

Francesca Pizzo · Inserm

Stanislas Lagarde · Inserm

Isabelle Lambert · Inserm

Anca Nica · Centre Hospitalier Universitaire de Rennes

Aileen McGonigal · Inserm

Bernard Giusiano · Inserm

Abstract

At the patient level, the performance of HFOs is weakened by the presence of strong physiological HFO generators. Fast ripples are not sensitive enough to be the unique biomarker of epileptogenicity. Nevertheless, combining HFOs and spikes using our proposed measure-the cross-rate-is a better strategy than using only one marker. Ann Neurol 2018;83:84-97.

Topics & Keywords

Epilepsy research and treatment EEG and Brain-Computer Interfaces Neuroscience and Neuropharmacology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 83, Issue 1, pp. 84-97

DOI: 10.1002/ana.25124

Field-Weighted Citation Impact: 10.91