Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells

2018136 citationsJournal Article

Authors

Jinlong He · Tianjin University of Traditional Chinese Medicine

Qiankun Bao · Chinese Academy of Sciences

Yan Zhang · Tianjin Medical University

Mingming Liu · Georgia State University

Huizhen Lv · Tianjin University of Traditional Chinese Medicine

Yajin Liu · Chinese Academy of Sciences

Yao Liu

Abstract

YAP binding sustained STAT3 in the nucleus to enhance the latter's transcriptional activity and promote angiogenesis via regulation of angiopoietin-2.

Topics & Keywords

Hippo pathway signaling and YAP/TAZ Wnt/β-catenin signaling in development and cancer Angiogenesis and VEGF in Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Research

Volume 122, Issue 4, pp. 591-605

DOI: 10.1161/circresaha.117.311950

Field-Weighted Citation Impact: 7.31