Single‐cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma

2018363 citationsJournal Articlehybrid Open Access

Authors

Hongping Zheng · Center for Cancer Research

Yotsawat Pomyen · Center for Cancer Research

Maria O. Hernandez · National Institutes of Health

Caiyi Li · National Institutes of Health

Ferenc Livák · National Institutes of Health

Wei Tang · National Institutes of Health

Hien Dang

Abstract

Our work provides unique perspectives into the biodiversity of CSC subpopulations, whose molecular heterogeneity further highlights their role in tumor heterogeneity, prognosis, and hepatic CSC therapy. (Hepatology 2018;68:127-140).

Topics & Keywords

Cancer Genomics and Diagnostics Cancer Cells and Metastasis Single-cell and spatial transcriptomics

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Hepatology

Volume 68, Issue 1, pp. 127-140

DOI: 10.1002/hep.29778

Field-Weighted Citation Impact: 10.96