Immune-Related Adverse Events Associated with Immune Checkpoint Blockade

20184,515 citationsReview

Authors

Matthew D. Hellmann · Cornell University

Abstract

The wide range of immune-related adverse effects associated with immune checkpoint blockade can complicate this effective therapy and limit its use in patients with cancer. This review surveys the adverse effects and their management.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Immune Cell Function and Interaction Colorectal Cancer Treatments and Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 378, Issue 2, pp. 158-168

DOI: 10.1056/nejmra1703481

Field-Weighted Citation Impact: 177.73

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