Five percent of healthy newborns have an ETV6-RUNX1 fusion as revealed by DNA-based GIPFEL screening

TO THE EDITOR: Pediatric acute lymphoblastic leukemia (ALL) is characterized by recurrent preleukemic chromosomal translocations that emerge frequently in utero.[1][1] The most common translocation t(12;21) occurs in 25% of B-cell precursor ALL and results in the formation of the chimeric