HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

2018149 citationsJournal Articlehybrid Open Access

Authors

Pascal Mutz · German Cancer Research Center

Philippe Metz · Heidelberg University

Florian A. Lempp · Heidelberg University

Silke Bender · German Cancer Research Center

Bingqian Qu · Heidelberg University

Katrin Schöneweis · Heidelberg University

Stefan Seitz ·

Abstract

In dHepaRGNTCP cells and PHHs, HBV evades the induction of IFN and IFN-induced antiviral effects. HBV infection does not rescue HCV from the IFN-mediated response.

Topics & Keywords

Hepatitis C virus research Hepatitis B Virus Studies Liver Disease Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gastroenterology

Volume 154, Issue 6, pp. 1791-1804.e22

DOI: 10.1053/j.gastro.2018.01.044

Field-Weighted Citation Impact: 11.90