Aberrant intestinal microbiota in individuals with prediabetes

2018461 citationsJournal Articlehybrid Open Access

Authors

Kristine H. Allin · Novo Nordisk Foundation

Valentina Tremaroli · University of Gothenburg

Robert Caesar · University of Gothenburg

Benjamin A. H. Jensen · University of Copenhagen

Mads V. Damgaard · University of Copenhagen

Martin Iain Bahl · Technical University of Denmark

Tine Rask Licht

Abstract

Collectively, our data show that individuals with prediabetes have aberrant intestinal microbiota characterised by a decreased abundance of the genus Clostridium and the mucin-degrading bacterium A. muciniphila. Our findings are comparable to observations in overt chronic diseases characterised by low-grade inflammation.

Topics & Keywords

Gut microbiota and health Diet and metabolism studies Gastrointestinal motility and disorders

UN Sustainable Development Goals

No povertyGood health and well-being

Publication Details

Published in: Diabetologia

Volume 61, Issue 4, pp. 810-820

DOI: 10.1007/s00125-018-4550-1

Field-Weighted Citation Impact: 16.30