The Effects of Netarsudil Ophthalmic Solution on Aqueous Humor Dynamics in a Randomized Study in Humans

2018113 citationsJournal Articlebronze Open Access

Authors

Arash Kazemi · Mayo Clinic

Jay W. McLaren · Mayo Clinic

Casey Kopczynski · Aerie Pharmaceuticals (United States)

Theresa Heah · Aerie Pharmaceuticals (United States)

Gary D. Novack · University of California, Davis

Arthur J. Sit · Mayo Clinic

Abstract

Once-daily dosing of netarsudil ophthalmic solution 0.02% lowered IOP through increasing trabecular outflow facility and reducing EVP. This suggests a combination of mechanisms that affect both the proximal and distal outflow pathways.

Topics & Keywords

Glaucoma and retinal disorders Retinal Diseases and Treatments Retinal Development and Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Ocular Pharmacology and Therapeutics

Volume 34, Issue 5, pp. 380-386

DOI: 10.1089/jop.2017.0138

Field-Weighted Citation Impact: 13.42