High complement levels in astrocyte‐derived exosomes of Alzheimer disease

2018376 citationsJournal Article

Authors

Gregory A. Jicha · University of Kentucky

Dimitrios Kapogiannis · National Institute on Aging

Abstract

ADE complement effector proteins in AD are produced by dysregulated systems, attain higher levels than in controls, and may potentially damage neurons in the late inflammatory phase of AD. Ann Neurol 2018;83:544-552.

Topics & Keywords

Neuroinflammation and Neurodegeneration Mechanisms Alzheimer's disease research and treatments Barrier Structure and Function Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 83, Issue 3, pp. 544-552

DOI: 10.1002/ana.25172

Field-Weighted Citation Impact: 16.83