Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress

2018175 citationsJournal Articlehybrid Open Access

Authors

Rong-Shuang Yuan · Beihua University

Xue Tao · Beihua University

Shuang Liang · Beihua University

Pan Yan · Beihua University

He Li · Beihua University

Jinghui Sun · Beihua University

Wenbo Ju · Beihua University

Abstract

SCAP has a protective effect on ethanol-induced liver injury in mice and cells, and the mechanism underlying may be via inhibiting the expression of CYP2E1 protein and then alleviating oxidative stress injury induced by ethanol.

Topics & Keywords

Alcohol Consumption and Health Effects Eicosanoids and Hypertension Pharmacology Drug-Induced Hepatotoxicity and Protection

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Biomedicine & Pharmacotherapy

Volume 99, pp. 537-542

DOI: 10.1016/j.biopha.2018.01.079

Field-Weighted Citation Impact: 6.82