Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis

2018124 citationsJournal Articlebronze Open Access

Authors

Yanbo Fan · University of Michigan

Haocheng Lu · University of Michigan

Wenying Liang · University of Michigan

Minerva T. Garcia-Barrio · University of Michigan

Yanhong Guo · University of Michigan

Ji Zhang · University of Michigan

Tianqing Zhu ·

Abstract

In summary, our data demonstrate that TFEB is a positive regulator of angiogenesis through activation of AMPKα and autophagy, suggesting that TFEB constitutes a novel molecular target for ischemic vascular disease.

Topics & Keywords

Angiogenesis and VEGF in Cancer Ubiquitin and proteasome pathways Nuclear Receptors and Signaling

Publication Details

Published in: Circulation Research

Volume 122, Issue 7, pp. 945-957

DOI: 10.1161/circresaha.118.312672

Field-Weighted Citation Impact: 5.48

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Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis

Authors

Abstract

Topics & Keywords

Publication Details