<i>Vital Signs</i>: Containment of Novel Multidrug-Resistant Organisms and Resistance Mechanisms — United States, 2006–2017

The proportion of Enterobacteriaceae infections that were CRE remained lower and decreased more over time than the proportion that were ESBL phenotype. This difference might be explained by the more directed control efforts implemented to slow transmission of CRE than those applied for ESBL-producing strains. Increased detection and aggressive early response to emerging antibiotic resistance threats have the potential to slow further spread.