Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa

2018366 citationsJournal Articlehybrid Open Access

Authors

Jeremy D. Keenan

Robin L. Bailey · London School of Hygiene & Tropical Medicine

Sheila K. West · Johns Hopkins University

Ahmed M. Arzika · United Nations Children's Fund Niger

John Hart · London School of Hygiene & Tropical Medicine

Jerusha Weaver · Johns Hopkins Medicine

Khumbo Kalua · Blantyre Institute for Community Ophthalmology

Abstract

Among postneonatal, preschool children in sub-Saharan Africa, childhood mortality was lower in communities randomly assigned to mass distribution of azithromycin than in those assigned to placebo, with the largest effect seen in Niger. Any implementation of a policy of mass distribution would need to strongly consider the potential effect of such a strategy on antibiotic resistance. (Funded by the Bill and Melinda Gates Foundation; MORDOR ClinicalTrials.gov number, NCT02047981 .).

Topics & Keywords

Global Maternal and Child Health Child Nutrition and Water Access Child and Adolescent Health

Publication Details

Published in: New England Journal of Medicine

Volume 378, Issue 17, pp. 1583-1592

DOI: 10.1056/nejmoa1715474

Field-Weighted Citation Impact: 69.92

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Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa

Authors

Abstract

Topics & Keywords

Publication Details